a decent per cent of any future revenues without any more cash commitment thru remaining testing etc.. 5m Cash in the bank is very useful too.. I added some this morning and had hoped for 20p today .. unlikely now i'm thinking.. so I'll probably trade out of some of this today but will keep a core holding here and think that the s/p market cap. feels still extremely low here.. so much room for future s/p growth .. assuming they continue to progress their prospective treatments incrementally towards market, of course .. DYOR of course
My error - I saw 27th and thought that it was today...not last month. Been in this for ages so no a downhill ride, and I don't check the BB very often - not until this morning. Glad I did as I'm quite encouraged by the news, albeit it being a month old.
· Cold infections did not affect trial patients' asthma in the INEXAS study as much as predicted, meaning that the drug's effects on severe exacerbations could not be determined
· Treatment with AZD9412 switched on antiviral responses in the lungs, improved morning peak flow (a measure of lung function), and was well tolerated
· The study however, did not meet AstraZeneca's predefined criteria for progression, and they have elected to return the rights to AZD9412 to Synairgen
· Synairgen will conduct further analysis of the data and determine future development routes
Southampton, UK - 27th April 2017: Synairgen plc (LSE: SNG), the respiratory drug discovery and development company, today provides an update on AZD9412 (inhaled interferon beta).
In October 2016 Synairgen provided the market with an update on the INEXAS trial of AZD9412, a novel, inhaled interferon beta that supports the immune system by correcting a deficiency which makes patients vulnerable to respiratory tract viral infections (primarily common cold viruses). The trial was stopped early due to a low severe exacerbation event rate which compromised an assessment of this endpoint (number of severe exacerbations).
Treatment with inhaled interferon beta did however switch on the lungs' antiviral defences (as measured by blood levels of the antiviral biomarker CXCL10), have a beneficial effect on lung function (Morning Peak Expiratory Flow: difference of 19.7 litres per minute average over the first 7 days of treatment (p=0.01)), and was well tolerated. Effects on biomarkers, lung function and the good tolerability profile were consistent with the Company's own Phase II trial (SG005).
The study did not however meet AstraZeneca's predefined criteria for progression, and they have elected to return the rights to AZD9412 to Synairgen.
Further analysis of samples from the trial is being completed by AstraZeneca. Data from this sample analysis and the clinical trial data will be licensed to Synairgen. Synairgen will complete the data analysis and will use this as a basis to determine the future direction of the programme.
Professor Stephen Holgate CBE, Medical Research Council Clinical Professor of Immunopharmacology at the University of Southampton, said: "We believe that the biomarker, lung function and safety data from this and our previous study continue to support the potential of inhaled interferon beta as a treatment for vulnerable patients whose disease control is badly affected when they get a cold. We are particularly interested in the potential for COPD, where exacerbations are associated with disease progression and an increased risk of dying. Since we licensed this programme to AstraZeneca, the weight of data linking viruses to COPD exacerbations has increased, and the link of colds to secondary bacterial infections has become widely accepted."
Richard Marsden, CEO of Synairgen, said: "We remain positive about the potential of inhaled interferon beta, particularly for patients with COPD who suffer due to respiratory viruses. Once we have completed the data analysis, we will provide an update on the programme and our plans for future development."
Bad me.... conferance call 2pm now... look what you guys made me do... yes "MADE" me do, the exact same way i MAKE people buy...
My game... lets add another dimension to it and ask...
Who would be unscrupulous enough to suggest that on a rising share price, if the company does not release an rns regards said rise it must mean good news is on the way ?????
Clue... same person who posts off topic tips...
Its now coming up to 12:30 and they`ve said nothing!!
That suggests that there is something in it.
My guess is that there has been an approach but the BOD think that the company is worth more, along with plenty of other people including myself.
So we wait for an update, they will have seen the massive volume over yesterday and today so will probably be meeting to decide how to respond.
Interesting times for this company."
Now, that is bad. Lol.... whatever way you try to dress that up, its naughty.... lol..
No news must mean an offer for the company has been made...
You couldnt make it up...
I am a fake.
I push SNG
I push VOG
I dont tend to push GKP because i am actually down about 80%on that, holding circa £287k shares (cost to me)
SNG... hmmmmmm. I pop into the Style on an occaisional Friday afternoon.
You know the style... on the corner of burgess road on the uni campus.
If you had something to say abot SNG that didnt make it the screaming buy it is, then i would maybe give your warning some credibility.
Maybe Richard Griffiths who recently increased his stake in SNG to 11% was taken in by me? Lol
Maybe the buy recs for VOG have also been in vain, and amongst other things the analysts putting a £1.70 target were also taken in by me?
Then my latest... "MWG" MODERN WATER...... i promote that from this week as a very strong buy.
Guess what? I am driving up to Guildford at 10am
I take my investing very seriously.
Maybe you could do the same instead of looking for conspiracy theories.
Maybe you could even buy some MWG??? But then again, maybe not. :-)
I bought some of these shares a while back so happy for someone to ramp if it pushes the price up; however I really doubt anyone will buy based on the back of a few posts by someone they do not know nor will the price be affected by the occasional bullish post.
Hi Disorder - I don't mind OT if either informative or funny; hate bickering slagging off peoples posts for the sake of it and people can make their own mind up about whether someone is pumping something or not.
Thanks for your views and I will research in due course but not looking to over invest in AIM, heavily invested in the US following Brexit and increase since Trump elected as I might not like the guy but the market does; however am keeping a close watch for downward correction.
Some people hate off topic posts.
I however quite like them if they are substantianted and stocks i can verify relatively easilly.
MWG is I believe such a stock.
I have recently bought some MWG
Having fulfilled some extensive research into the company I have formed the opinion that it is extremely well placed to start benefitting from some (if not all) of its offerings.
That, along with zero debt and costs under control it offers an excellent opportunity to benefit from some very decent rises.
A bit like VOG and certainly like SNG (Which by the way has now passed 30p from the 13p level I originallty said it was worth investigating.
Of course if others do research MWG and decide to get in then expect the sp to rise.
If they then decide to top slice profit expect it to retrace a little.
Some will consider this pumping, some will consider it a nudge in the right deirection with the ultimate decision on whether to buy or not there own choice.
I have acquired 500,000 MWG at prices ranging £0.0585 to £0.622
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